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Cancer 8 , 604617 (2008)

Afamelanotide is licensed for a rare photosensitivity disorder under tight specialist control

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Subsequently, beneficial effects of FOXO4-DRI have been demonstrated in various age-related models 6,7,8

Elegant studies from Blumberg and colleagues have also revealed that in specifically hematopoietic cells, FcRn has a role in antigen presentation [86,87,88] and binding of immune complexes (ICs) taken up by the activating Fc gamma (Fc) receptor IIa [89], which links it to the inflammatory potential of ICs and T cell activation [90,91,92]